- February 11 - Peggy Fleming wins Olympics figure skating gold medal, Grenoble, France.
- February 11 - Israeli-Jordan border clashes.
- February 11 - Madison Square Garden III closes, Madison Square Garden IV opens in New York.
- March 31 - American President Lyndon Johnson announces he will not seek re-election.
- April 23-April 30 - Student protesters at Columbia University in New York City take over administration buildings and shut down the university.
- April 4 - Martin Luther King, Jr. is assassinated by James Earl Ray in Memphis, Tennessee.
- May - Uprising in Paris nearly brings down the government
- June 5 - Robert F. Kennedy is assassinated by Sirhan Sirhan in Los Angeles, California.
- August 21 - Warsaw Pact nations invade Czechoslovakia
- August 22-August 30 - Police attack antiwar protesters in Chicago outside the Democratic Party convention
- Summer Olympic Games Mexico City Mexico
- Physics - Luis Walter Alvarez
- Chemistry - Lars Onsager
- Medicine - Robert W Holley, Har Gobind Khorana, Marshall W Nirenberg
- Literature - Yasunari Kawabata
- Peace - René Cassin