ACE inhibitor

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Any drug used in the treatment of congestive cardiac failure (CCF) that work by inhibiting the formation of the vasoconstrictor angiotensin II from angiotensin I by blocking the Angiotensin Converting Enzyme.

These drugs lowers arteriolar resistance and increases venous capacitance; increase cardiac output and index, stroke work and volume; lower renovascular resistance and lead to increased natriuresis (excretion of sodium in the urine).

There are also ACE inhibitors called vasopeptidase inhibitors.