O O RCOH + HNR' --> RCNR' + H2O H H acid amine amide water
All amides have the functional group:
O || - C - N - | H
An amide linkage is kinetically stable to hydrolysis. Amide linkages in a biochemical context are called peptide linkages. Amide linkages constitute a defining molecular feature of proteins, the secondary structure of which is due in part to the hydrogen bonding abilities of amides.